Prof. Laoise McNamara(PI)

Dr Laoise McNamara pictured at NUI GalwayPhotograph by Aengus McMahon
Prof. Laoise McNamara pictured at NUI Galway Photograph by Aengus McMahon

Prof. Laoise McNamara is a Profesor in Biomedical Engineering at the National University of Ireland, Galway. Her research group use multidisciplinary approaches to understand mechanobiology and how this process contributes to bone development and osteoporosis.

Prof. McNamara’s research group have developed novel multiphysics and multiscale computational modelling techniques and have applied these methods to derive an understanding of the mechanical stimuli that bone cells experience in vivo in healthy and osteoporotic bone tissue

Her research group use experimental techniques to identify the specific mechanosensation and mechanotransduction mechanisms by which bone cells sense mechanical stimuli. These studies have contributed a novel understanding of changes in bone mechanobiology during osteoporosis. This research has been applied to understand the role of mechanical stimulation in bone regeneration and she develops in vitro tissue regeneration strategies that exploit mechanobiological responses to overcome challenges in the field of bone tissue engineering.

Prof. McNamara collaborates with the medical device companies Stryker, Boston Scientific and Medtronic Vascular applying her expertise in computational and experimental biomechanics to the pre-clinical assessment of various surgical and minimally invasive devices.

Prof. McNamara’s research is informing the generation of novel therapeutic approaches for osteoporosis. Her research also strives to provide an understanding of the long term performance of transcatheter heart valve technologies for the treatment of aortic valve stenosis.

Prof. McNamara was awarded a European Research Council Starting Independent Researcher Award in 2011 and the SFI Investigators Grant in 2015. For her research she has been awarded the ‘Bone and Joint Decade’ New Investigator Award by the Orthopaedic Research Society, and the Harold B. Frost Young Investigator Award by the American Society for Bone and Mineral Research (ASBMR).

Prof. McNamara’s research has published more than 70 research articles in various high Impact Factor journals; PNAS, European Cells and Materials, the Journal of the Royal Society Interface, Bone, Tissue Engineering Part A and the Biophysical Journal, among many others.

Prof. McNamara is a reviewer for over 20 peer-reviewed international journals. She has also acted as a Royal Academy of Engineering (UK) reviewer for the Irish Research Council for Science and Engineering Technology (IRCSET) Postdoctoral Fellowships scheme.

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